THEME02-1-1107-2011/2013

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02-1-1107-2011/2013

Priority:

Status:

New

Development and Creation of the Prototype of a Complex for Radiotherapy and Applied Researches on Beams of Heavy Ion on the Nuclotron-M

Leaders:

S.I. Tyutyunnikov
J. Ruzicka
M.G.Kadykov

Participating Countries, Institutes and International organizations:
Australia, Armenia, Belarus, Bulgaria, Czech Republic, India, Germany, Greece, Kazakhstan, Moldova, Mongolia, Poland, Romania, Russia, Serbia, Slovak Republic, Ukraine.

Scientific Programme:
The main goal of the theme is creation of Medical-biological complex on the base of accelerator of protons and ions of VBLPHE and carrying out research program on the field of medical biology and oncology therapy. On the first stage it is considered development of new equipment for ion beam shaping and monitoring. Research programme on the field of influence of nano-structual complexes of heavy metals on radiating damages of biological cells, research of local destruction of cancer cells by/upon microwave/super frequency heating of metal nano-clusters. Investigation of some new aspects of radioactive waste transmutation and nuclear energy production.

Expected main results:

Development of transportation channel for carbon ions with energy E=200-250 MeV/nucl with the beam size of 2-3 mm produced by the Nuclotron and by the Booster of the NICA complex. Calculations and creation of the fast scanning system of this beam in XY-directions, manufacture and adjustment of the diagnostic equipment for the control of energy and spatial characteristics of carbon beam. The ultimate goal is a carrying out of phantom irradiations aimed at to define the necessary dose characteristics for therapy of cancer tumors.
Investigation of neutronic characteristics of the assemblies: "a lead target plus uranium blanket" (the installation "Energy plus Transmutation"), "a uranium target plus lead moderator" (the installation
"E+T/Quinta"), "a lead target plus graphite moderator" (the installation "GAMMA-3") and extended natural uranium target +/- graphite moderator ("EZHIK") under protons and deuterons irradiation by Nuclotron beams with energy from 0,6 up to 6,0 GeV.
Obtaining information on neutron energy spectra and their spatial distribution. Investigation of opportunities for nuclear energy production and simultaneous transmutation of radioactive wastes on the basis of semi--infinite targets from natural uranium and thorium.

Expected main results in 2011:

Calculations of scanning and focusing systems of carbon ion beam.
An engineering of the system for spatial monitoring of the carbon beam on the target in a real time mode, a creation of the model of this system and its test on the Nuclotron beam.
Development and manufacturing of detector prototypes for measurement of carbon ion energy in the range E=100-250 MeV/nucl.
Development of a technical project for the channel output beam of carbon nuclei of the booster NICA in the experimental zone for a prototype installation for radiocarbom therapy.
Research on model structures efficiency of heating by microwave radiation from FEL ferro-magnetic nanocluster on the basis of cobalt with a view to their possible use to destroy cancer cells.
Study of generation and multiplication of neutrons in heavy targets (Pb and U) under irradiation by proton and deutron beams of the Nuclotron within the energy interval (0,6-6,0) GeV. Data taking on neutron energy spectra and their spatial distribution and radioactive waste transmutation rates in uranium and lead targets with uranium blanket ("Energy plus Transmutation" and "E+T/Quinta") and in a lead target witn graphite moderator ("GAMMA-3" setup). Study of transmutation characteristics of highly toxic long-lived radioactive waste products ( ¹²⁹I, ²³⁷Np, ²³⁸Pu, ²³⁹Pu and ²⁴¹Am) in neutron field of above mentioned targets.
Study of structual material properties in neutron fields.

List of projects:
	Project	Leader	Priority (period of realisation)
1.	Development of prototype units for a Complex of Carbon Radiotherapy	S.I. Tyutyunnikov	1 (2010-2012)
2.	Study of deep subcritical electro-nuclear systems and feasibility of their application for energy production and radioactive waste transmutation	S.I. Tyutyunnikov	1 (2011-2013)

List of Activities

Activity or Experiment

Leader

Status

Laboratory

Responsible
person

Leading Researchers
and number of participants

Carrrying out of calculations of beam dynamics and design of ion-optical system for a transportation and focusing of carbon ion beam

I.P. Yudin

Realization

VBLHEP

V.S. Alexandrov + 2 pers.
P.A. Rukoyatkin + 3 pers.

The research and developments
of the system prototype for 20 scanning of carbon ion beam

A.A. Fateev
N.I. Lebedev

Realization

Development and manufacturing of two-dimensional detector system for spatial monitoring of carbon ion beam in real time mode and creation of beam control systems in the scanning mode.

S.A. Movchan

Realization

VBLHEP

A.V. Vishnevsky
A.V.Pilyar

Research of efficiency of biological cell destruction in metal nanoclusters of various structure by the MICROWAVE heating.
Research of its properties in dependence on duration and power of radiation spectrum.

S.I. Tyutyunnikov
S.N. Sedykh
G.M.Arzumanyan

Realization

VBLHEP

A.K. Kaminsky
E.A. Perelshtein
V.N. Shalyapin
I.A. Kryachko
V.V. Efimov
Yu.S. Kovalev

Preparation of the project of the medical-biological complex on the basis of the Booster of the NIKA project

S.I. Tyutyunnikov
J. Ruzicka
I.P. Yudin

Realization

VBLHEP

V.A. Mikhaylov + 3 pers.
I.P. Yudin + 3 pers.

Study of neutron generation and transmutation rates in heavy targets under proton and deuteron irradiation with the beam energy up to 6 GeV. Research of structual changes of materials in the neutron fields

M.G. Kadykov
V.S. Pronskikh

Data taking
Data processing
Upgrade

VBLHEP

A.A. Baldin + 5 pers.

DLNP

J. Adam + 4 pers.

LRB

V.Yu. Shchegolev + 2 pers.

FLNP

N.A. Gundorin + 4 pers.

LIT

A. Polansky + 2 pers.

Collaboration
Country or international organization	City	Institute or Laboratory
Armenia	Yerevan	YSU
Australia	Sydney	Univ.
Belarus	Minsk	JIPNR-Sosny NASB
	Minsk	IP NASB
Bulgaria	Sofia	INRNE BAS
Czech Republic	Rez	NRI
Germany	Darmstadt	TU Darmstadt
	Marburg	Univ.
	Julich	FZJ
Greece	Thessaloniki	AUTH
India	Mumbai	BARC
	Jaipur	Univ.
Kazakhstan	Almaty	PTI MS-NAS RK
		INP NNC RK
Moldova	Chisinau	IAP ASM
Mongolia	Ulaanbaatar	IPT MAS
Poland	Warsaw	WUT
	Krakow	NINP PAS
	Otwock-Swierk	IAE
Russia	Obninsk	MRRC RAMS
		IPPE
	Dubna	RDH-9
		BSINP MSU
	Tomsk	TPU
Romania	Bucharest	ISS
		UMF "Carol Davila"
		INCDIE ICPE-CA
Serbia	Belgrade	INS "VINCA"
Slovak Republic	Bratislava	SOSMT
		CU
Ukraine	Kharkov	KFTI NASU
	Uzhgorod	UNU

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