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04-2-1132-2017/2019
Priority:1
Status: New

Biomedical and Radiation-Genetic Studies Using Different Types of Ionizing Radiation


Leader:     G.V. Mitsyn
Deputy:     S.V. Shvidky

Participating Countries and International Organizations:
Czech Republic, India, Poland, Romania, Russia.

Scientific Programme:
Medico-biological and clinical research for the proton radiotherapy of cancer patients. Formatian of experimental data base in the field of radiation mutagenesis in the animal germ cells.

Expected main results in 2017:
  • Continuation of clinical researches on proton therapy of cancer patients in Room 1. Evaluation of the effectiveness of the conducted radiation treatment of different neoplasms.

  • Work to increase the functional capability of the developed 3D treatment planning software and its clinical tests in the treatment sessions.

  • Test of the prototype equipment for the dynamic conformal irradiation of deep-seated tumours with the proton beam.

  • Development and improvement of detectors and tools for the clinical dosimetry of the medical hadron beams.

  • Exploration of the possibilities of laser radioprotection against damage after exposure to ionizing radiation on mouse fibroblast cells with the application of laser module with a wave length of 532 nm.

  • Investigations of the molecular spectra of gene mutations induced by different quality ionizing radiation in animal germ cells.

List of projects:
  Project Leader Priority
(period of realisation)
1. Further development of methods,
technologies, schedule modes and
delivery of radiotherapy
G.V. Mitsyn 1   (2017-2019)
2. RADIOGENE: Experimental
justification of radiation genetic risk
estimation according to the frequency of
heritable DNA changes in human and
animal structural genes
I.D. Alexandrov 1   (2017-2019)

List of Activities
  Activity or Experiment Leaders
Status
  Laboratory or other
Division of JINR
Responsible person
Main researchers
1. Further development of methods,
technologies, schedule modes and
delivery of radiotherapy
G.V. Mitsyn
K.Sh. Voskanyan
R&D
  DLNP A.V. Agapov, I.V. Alexandrova, V.M. Breyev, D.M. Borovich, V.N. Gaevsky, G.V. Donskaya, Ye.I. Luchin, I.I. Klochkov, I.Ye. Miller, A.G. Molokanov, K. Oancea, S.A. Pisareva, M.A. Tseytlina, K.N. Shipulin, A.V. Rzyanina
2. RADIOGENE: Experimental
justification of radiation-genetic
risk estimation according to the
frequency of heritable DNA
changes in human and animal
structural genes
I.D. Alexandrov
R&D
  DLNP M.V. Alexandrova, K.P. Afanasyeva, S.V. Korablinova, L.N. Korovina, Ye.V. Kravchenko, A.N. Rusakovich

Collaboration
Country or International
Organization
City Institute or Laboratory
Czech Republic Rz{UJV tab{
India Mumbai BARC
New Delhi IUAC
Poland Krakow NINP PAS
Otwock-Swierk NCBJ
Poznan GPCC
Romania Bucharest UMF
UB
Russia Moscow VIGG RAS
IBMP RAS
RMAPE
Dubna RDH-9
Rostov-on-Don SFedU

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