The present review is devoted to the spin-dependent experiments prepared at the JINR Veksler-Baldin Laboratory of High Energies and carried out at the Synchrophasotron or Nuclotron accelerators. The acceleration of polarized deuterons, experiments using the internal targets, the beam extraction and the polarimetry are briefly described. Then, representative experiments using either the extracted deuteron beam or secondary beams of polarized nucleons produced by polarized deuterons, are considered. Three current experiments: DELTA-SIGMA, DELTA, pp SINGLET, and recently BES, require the polarized nucleon beams in conjunction with the Dubna polarized proton target. Already available Ds_L(np) results from the first experiment show an unexpected energy dependence. The experiment DELTA should investigate the nucleon strangeness. The aim of the pp SINGLET is to study a possible resonant behavior of the spin-singlet pp-scattering amplitude. BES proposes the measurement of the complete experiment in dp backward elastic scattering. For all other Dubna experiments, unpolarized nucleon or nuclei targets are used. The polarized deuteron beam allows one to determine spin-dependent observables necessary for understanding the deuteron structure, as well as the nucleon substructure. One part of investigations concerns deuteron break-up reactions and deuteron-proton backward elastic scattering. A considerable amount of data was obtained in this domain. Another part is dedicated to the measurements of the same spin-dependent observables in a "cumulative" region. Interesting results were obtained for proton or pion productions in inclusive and semi-inclusive measurements. In the field of inelastic deuteron reactions, the analyzing-power measurements were performed in the region covering Roper resonances. Many existing models are in disagreement with observed momentum dependences of different results. Finally, the proton-carbon analyzing-power measurements extended the momentum region of rescattering observables. Some inclusive Dubna results are compared to exclusive Saclay data and to lepton-deuteron measurements. Finally, the pC and pCH₂ analyzing-power data extended the momentum region of rescattering observables. Most of the JINR LHE experiments are carried out in the framework of a large international collaboration.

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