Modern
Trends and Developments in Raman Microspectroscopy
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Leaders: |
G.M. Arzumanyan |
Participating
countries and international organizations:
Armenia, Belarus, Bulgaria, Cuba, Egypt, Poland, Romania, Russia, Slovakia, Ukraine, Uzbekistan.
Issues
addressed and main goals of research:
Fundamental and applied research in the field of spontaneous and nonlinear Raman microspectroscopy aimed at highly sensitive biosensing. Study of mechanisms and nature of surface-enhanced Raman scattering (SERS) taking into account the anomalous ratio of line intensities in the anti-Stokes and Stokes spectral regions. Development of ultralow-frequency Raman spectroscopy for biomedical purposes, including early diagnostics.
Expected
results in the current year:
Development of a technique for simultaneous registration of Stokes and anti-Stokes components in SERS spectra.
Revealing a possible nonlinear dependence of SERS spectra on the pump power.
Detailed characterization of Raman spectra of liposomes with embedded proteins.
Search and identification of the Raman marker of NETosis for the purposes of early diagnostics.
Acquisition and registration of spectra using optics adapted for low-frequency Raman spectroscopy.
List of projects: |
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Project |
Leaders |
Priority |
|
1. |
Raman
microspectroscopy |
G.M.
Arzumanyan |
1 (2021-2023) |
List of Activities: |
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|
Activity or Experiment |
Leaders |
Status |
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Laboratory
or other |
Main researchers |
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1. |
Study of the features of Stokes and >anti-Stokes components of SERS spectra from analyte molecules in order to understand the processes of enhancement in SERS spectroscopy
|
G.M. Arzumanyan |
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FLNP |
K.Z. Mamatkulov, I.A. Morkovnikov, 2 engineers
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2. |
Determination
of the range of pump intensities for recording reproducible
|
G.M.
Arzumanyan |
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FLNP
|
M.Yu. Vorobyeva, S.P. Marmakov, 1 engineer
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3. |
Stabilization
of membrane proteins
|
G.M.
Arzumanyan |
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|
FLNP
|
K.Z. Mamatkulov, M.Yu. Vorobyeva, A. Damir
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4. |
Testing
the technique for obtaining
|
K.Z.
Mamatkulov |
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|
FLNP
|
M.Yu. Vorobyeva, A. Damir, 2 engineers
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5. |
Study of the influence of lipid environment on the structure of membrane protein |
G.M.
Arzumanyan |
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|
FLNP |
K.Z. Mamatkulov, M.Yu. Vorobyeva, K.Sh. Voskanyan, 1 engineer, 2 laboratory assistants
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6. |
Search for spectral / Raman markers of NETosis
|
G.M.
Arzumanyan |
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FLNP |
K.Z. Mamatkulov, M.Yu. Vorobyeva, 1 engineer, 2 laboratory assistants
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7. |
Study
of mechanisms of sterile activation |
G.M. Arzumanyan K.Z. Mamatkulov |
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FLNP
|
M.Yu. Vorobyeva, K.Sh. Voskanyan, A. Damir
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8. |
Mastering
the technique of ultra-low frequency Raman spectroscopy |
G.M.
Arzumanyan
|
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|
FLNP |
M.Yu. Vorobyeva, S.P. Marmakov, 2 engineers |
Collaboration
Country or International Organization |
City |
Institute or laboratory |
Armenia |
Yerevan |
Foundation ANSL |
Belarus |
Minsk |
BSUIR |
|
|
SOL instruments |
Bulgaria |
Sofia |
ISSP BAS |
Cuba |
Havana |
InSTEC |
Egypt |
Giza |
CU |
Poland |
Krakow |
JU |
Romania |
Cluj-Napoca |
INCDTIM |
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Magurele |
NIMP |
Russia |
Moscow |
GPI RAS |
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LMPR MONIKI |
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MSU |
Slovakia |
Kosice |
UPJS |
Ukraine |
Donetsk |
DonNU |
Uzbekistan |
Jizzakh |
JSPI |
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